SMAD4 Recombinant Rabbit mAb (SDT-168-62),specification,price,image-Bio-Equip in China

Product Detail
Company Profile

Product Specification

Host	Rabbit
Antigen	Smad4
Synonyms	Mothers against decapentaplegic homolog 4, MAD homolog 4, Mothers against DPP homolog 4, Deletion target in pancreatic carcinoma 4, SMAD 4, Smad4, hSMAD4
Immunogen	Synthetic Peptide
Location	Cytoplasm
Accession	Q13485
Clone Number	SDT-168-62
Antibody Type	Recombinant mAb
Application	WB, IHC-P, ICC, FC
Reactivity	Hu
Predicted Reactivity	Bv, Pg, Rt, Ms
Purification	Protein A
Concentration	0.5 mg/ml
Conjugation	Unconjugated
Physical Appearance	Liquid
Storage Buffer	PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300
Stability & Storage	12 months from date of receipt / reconstitution, -20 °C as supplied

Dilution

application	dilution	species
WB	1:1000
FC	1:500
ICC	1:100
IHC-P	1:100

Background

SMAD (mothers against decapentaplegic homologs) molecules are the core components in TGF-β signaling pathway. TGF-β binding to its receptor induces phosphorylation and activation of receptor-regulated SMADs (R-SMADs), SMAD2 and SMAD3, which subsequently associate with their partner SMAD4 and translocate from cytoplasm to nucleus. Formation of R-SMAD–SMAD4 complexes is essential in signaling of most TGF-β family members.