Human IgG3 F(c) Mouse mAb (S-460-1),specification,price,image-Bio-Equip in China

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Product Specification

Host	Mouse
Antigen	Human IgG3
Synonyms	Immunoglobulin heavy constant gamma 3, HDC, Heavy chain disease protein, Ig gamma-3 chain C region, IGHG3
Immunogen	Synthetic Peptide
Location	Secreted, Cell membrane
Accession	P01860
Clone Number	S-460-1
Antibody Type	Mouse mAb
Isotype	IgG2b,k
Application	ELISA, WB, IHC-P
Reactivity	Hu
Purification	Protein A
Concentration	2 mg/ml
Conjugation	Unconjugated
Physical Appearance	Liquid
Storage Buffer	PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300
Stability & Storage	12 months from date of receipt / reconstitution, -20 °C as supplied

Dilution

application	dilution	species
WB	1:1000	null
IHC-P	1:2000	null

Background

The intact antibody of human immunoglobulin (IgG) is composed of the fragment for antigen binding (Fab) and the crystallizable fragment (Fc) for binding of Fcγ receptors. Among the four subclasses of human IgG (IgG1, IgG2, IgG3, IgG4), which differ in their constant regions, particularly in their hinges and CH2 domains, IgG1 has the highest FcγR-binding affinity, followed by IgG3, IgG2, and IgG4 [PMID: 32370812].