sFlt-1/VEGF Receptor 1 Recombinant Rabbit mAb (SDT-233-29),specification,price,image-Bio-Equip in China

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Product Specification

Host	Rabbit
Antigen	sFlt-1/VEGF Receptor 1
Synonyms	VEGFR-1, FRT
Immunogen	Recombinant Protein
Location	Secreted
Accession	P17948-2
Clone Number	SDT-233-29
Antibody Type	Recombinant mAb
Application	IHC-P
Reactivity	Hu
Purification	Protein A
Concentration	0.25 mg/ml
Conjugation	Unconjugated
Physical Appearance	Liquid
Storage Buffer	PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300
Stability & Storage	12 months from date of receipt / reconstitution, -20 °C as supplied

Dilution

application	dilution	species
IHC-P	1:1000	null

Background

Vascular endothelial growth factor (VEGF) represents a growth factor with important pro-angiogenic activity, having a mitogenic and an anti-apoptotic effect on endothelial cells, increasing the vascular permeability, promoting cell migration, etc. VEGF binds to tyrosine kinase cell receptors (VEGFRs): VEGFR-1 [Fms-like tyrosine kinase 1 (Flt-1)], VEGFR-2 [kinase insert domain receptor (KDR) in human; fetal liver kinase 1 (Flk-1) in mouse] and VEGFR-3 [Fms-like tyrosine kinase 4 (Flt-4)]. While VEGFR-1 and VEGFR-2 are expressed predominantly on vascular endothelial cells, VEGFR-3 is expressed especially on lymphatic endothelial cells [PMID: 30173249].