S-RMab® FOXP3 Recombinant Mouse mAb (SDT-R149),specification,price,image-Bio-Equip in China

Product Detail
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Product Specification

Host	Mouse
Antigen	FOXP3
Synonyms	Forkhead box prote 1, Forkhead box protein P3, Scurfin
Immunogen	N/A
Location	Nucleus
Accession	Q9BZS1
Clone Number	SDT-R149
Antibody Type	Recombinant mAb
Isotype	IgG1
Application	WB, IHC-P
Reactivity	Hu
Purification	Protein G
Concentration	2 mg/ml
Tag	N/A
Physical Appearance	Liquid
Storage Buffer	PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300
Stability & Storage	12 months from date of receipt / reconstitution, -20 °C as supplied

Dilution

application	dilution	species
WB	1:1000
IHC-P	1:500

Background

FOXP3 is a transcription factor, which belongs to the family of FOX protein. FOXP3 was initially discovered in regulatory T cells and supposed to play a significant role in the process of regulatory T cell differentiation. Increasing evidence has shown that FOXP3 is also expressed in tumor cells. In some types of human cancers, the expression of FOXP3 is upregulated, and it can promote the development of cancers, leading to a poor prognosis [PMID: 30630091].