Antithrombin III Recombinant Rabbit mAb (SDT-294-211),specification,price,image-Bio-Equip in China

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Product Specification

Host	Rabbit
Antigen	Antithrombin III
Synonyms	ATIII, Serpin C1
Immunogen	Recombinant Protein
Location	Secreted, Extracellular space
Accession	P01008
Clone Number	SDT-294-211
Antibody Type	Recombinant mAb
Application	WB, IP
Reactivity	Hu
Cross Reactivity	Does not recognize thrombin, PIC complex, tPA-PAI-1 complex
Purification	Protein A
Concentration	0.5 mg/ml
Tag	N/A
Physical Appearance	Liquid
Storage Buffer	PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300
Stability & Storage	12 months from date of receipt / reconstitution, -20 °C as supplied

Dilution

application	dilution	species
WB	1:1000
IP	1:50

Background

Antithrombin III (AT III) is primarily a potent anticoagulant with independent anti-inflammatory properties. AT III irreversibly inhibits serine proteases (e.g. activated factor X and thrombin) in a one-to-one ratio, with the generation of protease–AT III complexes. Heparin prevents AT III from interacting with the endothelial cell surface by binding to sites on the AT III molecule, competing for the AT III binding site, and reducing AT III’s ability to interact with its cellular receptor [PMID: 26862016].