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Home >Products> Reagents >Antibody> Beta III tubulin Recombinant Rabbit mAb (SDT-251-28)
Beta III tubulin Recombinant Rabbit mAb (SDT-251-28)
Beta III tubulin Recombinant Rabbit mAb (SDT-251-28)
Origin of place Singapore
Model S0B0089-25ul
Supplier ANT BIO PTE.LTD.
Price 100
Hits 2
Updated 8/25/2025
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Product Specification


HostRabbit
AntigenBeta III tubulin
SynonymsTubulin beta-3 chain, Tubulin beta-4 chain, Tubulin beta-III
ImmunogenSynthetic Peptide
LocationCytoplasm, Cytoskeleton
AccessionQ13509
Clone NumberSDT-251-28
Antibody TypeRecombinant mAb
ApplicationWB, IHC-P, ICC, ICFCM, IP
ReactivityHu, Ms, Rt
PurificationProtein A
Concentration0.05 mg/ml
Physical AppearanceLiquid
Storage BufferPBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300
Stability & Storage12 months from date of receipt / reconstitution, -20 °C as supplied.

Dilution


applicationdilutionspecies
WB1:1000-1:5000
IHC-P 1:200
ICFCM1:50
ICC1:50
IP1:25

Background

Beta III-tubulin is frequently overexpressed in human tumors and is associated with resistance to microtubule-targeting agents, tumor aggressiveness, and poor patient outcome [PMID: 34364992 IF: 9.7 Q1 ]. In prostate cancer, βIII-tubulin expression is strongly associated with both TMPRSS2: ERG rearrangement, ERG expression and PTEN deletions, three key oncogenetic features of aggressive prostate cancer [PubMed: 24378408]. Also, colorectal cancer is more aggressive in young male patients in whom testosterone elevation and activation of TUBB3 are connected with poor outcome [PubMed: 23637935].

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