MEK1 Recombinant Rabbit mAb (SDT-308-32),specification,price,image-Bio-Equip in China

Product Detail
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Product Specification

Host	Rabbit
Antigen	MEK1
Synonyms	Dual specificity mitogen-activated protein kinase kinase 1, MAP kinase kinase 1, MAPKK 1, MKK1, ERK activator kinase 1, MAPK/ERK kinase 1
Immunogen	Synthetic Peptide
Location	Cytoplasm, Cytoskeleton, Nucleus, Membrane
Accession	Q02750
Clone Number	SDT-308-32
Application	WB, IHC-P, ICC, ICFCM, IP
Reactivity	Hu
Purification	Protein A
Concentration	0.5 mg/ml
Physical Appearance	Liquid
Storage Buffer	PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300
Stability & Storage	12 months from date of receipt / reconstitution, -20 °C as supplied.

Dilution

application	dilution	species
WB	1:1000-1:10000	null
IHC-P	1:500	null
ICC	1:1000	null
IP	1:50	null
ICFCM	1:500	null

Background

Mitogen-activated protein kinase kinases 1 and 2 (MEK1/2) are the crucial part of the RAS-RAF-MEK-ERK pathway (or ERK pathway), which is involved in the regulation of various cellular processes including proliferation, survival, and differentiation et al. Targeting MEK has become an important strategy for cancer therapy, and 4 MEK inhibitors (MEKis) have been approved by FDA to date [PMID: 33774345].