SPARC Recombinant Rabbit mAb (SDT-R136),specification,price,image-Bio-Equip in China

Product Detail
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Product Specification

Host	Rabbit
Antigen	SPARC
Synonyms	BM-40, Osteonectin, ON, Secreted protein acidic and rich in cysteine
Immunogen	N/A
Location	Secreted, Extracellular matrix, Basement membrane
Accession	P09486
Clone Number	SDT-R136
Application	WB, IHC-P, IP
Reactivity	Hu
Purification	Protein A
Concentration	0.5 mg/ml
Physical Appearance	Liquid
Storage Buffer	PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300
Stability & Storage	12 months from date of receipt / reconstitution, -20 °C as supplied

Dilution

application	dilution	species
WB	1:1000	null
IHC-P	1:2000	null
IP	1:50	null

Background

SPARC, also referred to as osteonectin or basement membrane protein 40 (BM-40), is a ~32 kDa calcium-binding matricellular protein [PMID: 22249026, PMID: 25064829]. At one time SPARC was thought to be expressed specifically in mineralized tissues (thus the name osteonectin) but was subsequently demonstrated to have a much wider expression pattern in both mineralized and non-mineralized tissues [PMID: 7034958]. Typically, expression of SPARC is closely aligned with that of fibrillar collagens such as collagen type I. The protein component of the pre-mineralized bone matrix (osteoid) is composed mainly of collagen type I (94%) and a number of noncollagenous proteins.