CD8α Recombinant Mouse mAb (SDT-126-8),specification,price,image-Bio-Equip in China

Product Detail
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Product Specification

Host	Mouse
Antigen	CD8α
Synonyms	T-lymphocyte differentiation antigen T8/Leu-2, T-cell surface glycoprotein CD8 alpha chain, MAL, CD8a
Immunogen	Synthetic Peptide
Location	Cell membrane
Accession	P01732
Clone Number	SDT-126-8
Antibody Type	Mouse mAb
Isotype	IgG1,k
Application	IHC-P
Reactivity	Hu
Purification	Protein G
Concentration	2 mg/ml
Physical Appearance	Liquid
Storage Buffer	PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300
Stability & Storage	12 months from date of receipt / reconstitution, -20 °C as supplied

Dilution

application	dilution	species
IHC-P	1:2000

Background

CD8A encodes the CD8 alpha chain of the αβT cells, proposed as a quantifiable indicator for CD8+ CTL recruitment or activity assessments and a robust biomarker for responses to anti-PD-1/PD-L1 therapy.In NK-cells, the presence of CD8A homodimers at the cell surface provides a survival mechanism allowing conjugation and lysis of multiple target cells. CD8A homodimer molecules also promote the survival and differentiation of activated lymphocytes into memory CD8 T-cells.