Product SpecificationHost | Mouse | Antigen | CD62L | Synonyms | L-selectin; CD62 antigen-like family member L; Leukocyte adhesion molecule 1 (LAM-1); Leukocyte-endothelial cell adhesion molecule 1 (LECAM1); Lymph node homing receptor; Lymphocyte antigen 22 (Ly-22); Lymphocyte surface MEL-14 antigen; Lnhr; Ly-22; Sell | Location | Cell membrane | Accession | P30836 | Clone Number | S-R605 | Antibody Type | Mouse mAb | Isotype | IgG1,k | Application | FCM | Reactivity | Rt | Positive Sample | Lewis Rat splenocytes | Purification | Protein G | Concentration | 2 mg/ml | Conjugation | Unconjugated | Physical Appearance | Liquid | Storage Buffer | PBS pH7.4 | Stability & Storage | 12 months from date of receipt / reconstitution, 2 to 8 掳C as supplied. |
Dilutionapplication | dilution | species | FCM | 1:2000 | Rt |
BackgroundCD62L, also known as L-selectin, is a type-I transmembrane glycoprotein and a member of the selectin family of adhesion molecules. It is expressed on most circulating leukocytes, including T cells, B cells, and neutrophils. CD62L plays a crucial role in leukocyte adhesion and migration, particularly in the process of lymphocyte homing to secondary lymphoid organs such as lymph nodes. It mediates the initial rolling of leukocytes on endothelial cells, which is a key step in the recruitment of immune cells to sites of inflammation. Additionally, CD62L is a marker for central memory T cells, which have the ability to rapidly respond to antigen re-exposure. Its expression levels can also indicate the differentiation state of certain immune cells and is involved in various immune responses. bio-equip.cn
AntBio is a biotechnology group company dedicated to serving life sciences, aiming to help scientists accelerate research and improve work efficiency. AntBio provides comprehensive and high-quality reagent tools for basic research, drug development, and diagnosis, including research grade antibodies, proteins, biochemical reagents, and assay kits. These research tools are widely used in different segments of life science research. The group company currently consists of three brands, Absin, Starter-Bio and UA-Bio.
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