Rat Anti-Mouse CD184 Antibody (S-R670),specification,price,image-Bio-Equip in China

Product Detail
Company Profile

Product Specification

Host	Rat
Antigen	CD184
Synonyms	C-X-C chemokine receptor type 4; CXC-R4; CXCR-4; Fusin; Leukocyte-derived seven transmembrane domain receptor (LESTR); Pre-B-cell-derived chemokine receptor (PB-CKR); Stromal cell-derived factor 1 receptor (SDF-1 receptor); Cmkar4; Lestr; Sdf1r; Cxcr4
Location	Lysosome, Cell membrane, Cell junction
Accession	P70658
Clone Number	S-R670
Antibody Type	Rat mAb
Isotype	IgG2b,k
Application	FCM
Reactivity	Ms
Positive Sample	C57BL/6 mouse thymocytes
Purification	Protein G
Concentration	2 mg/ml
Conjugation	Unconjugated
Physical Appearance	Liquid
Storage Buffer	PBS pH7.4
Stability & Storage	12 months from date of receipt / reconstitution, 2 to 8 掳C as supplied.

Dilution

application	dilution	species
FCM	1渭g per million cells in 100渭l volume	Ms

Background

CD184, also known as CXCR4 or Fusin, is a seven-transmembrane G protein-coupled receptor that plays a crucial role in various physiological processes. It is widely expressed on hematopoietic cells, including lymphoid and myeloid precursor cells, megakaryocytes, and endothelial cells. Its natural ligand is stromal cell-derived factor-1 (SDF-1), a C-X-C chemokine that induces chemotaxis and enhances intracellular signaling through calcium ion influx and MAPK activation.