Huntingtin Recombinant Rabbit mAb (S-1481-147),specification,price,image-Bio-Equip in China

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Product Specification

Host	Rabbit
Antigen	Huntingtin
Synonyms	Huntington disease protein (HD protein); HD; IT15; HTT
Immunogen	Synthetic Peptide
Location	Cytoplasm, Nucleus
Accession	P42858
Clone Number	S-1481-147
Antibody Type	Recombinant mAb
Isotype	IgG
Application	WB, ICC
Reactivity	Hu, Ms, Rt
Positive Sample	HeLa, SH-SY5Y, Neuro-2a, mouse brain, PC-12, rat brain
Purification	Protein A
Concentration	2 mg/ml
Conjugation	Unconjugated
Physical Appearance	Liquid
Storage Buffer	PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300
Stability & Storage	12 months from date of receipt / reconstitution, -20 掳C as supplied

Dilution

application	dilution	species
WB	1:1000	Hu, Ms, Rt
ICC	1:2000	Hu

Background

Huntingtin (HTT) is a large soluble protein composed of approximately 3144 amino acids, with a molecular weight of around 348 kDa. It is highly expressed in the central nervous system, particularly in neurons of the cerebral cortex and hippocampus. Huntingtin plays crucial roles in various cellular processes, including clathrin-mediated endocytosis, axonal transport, and synaptic signal transduction. It also helps protect neurons from apoptosis.