Biotin Rat Anti-Mouse CD3 Antibody (17A2),specification,price,image-Bio-Equip in China

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Product Specification

Host	Rat
Antigen	CD3
Synonyms	T-cell surface glycoprotein CD3 zeta chain; T-cell receptor T3 zeta chain; CD247; Cd3z; Tcrz
Location	Cell membrane
Accession	P24161
Clone Number	17A2
Antibody Type	Rat mAb
Isotype	IgG2b
Application	FCM
Reactivity	Ms
Positive Sample	C57BL/6 mouse splenocytes
Purification	Protein G
Concentration	0.2 mg/ml
Conjugation	Biotin
Physical Appearance	Liquid
Storage Buffer	PBS pH7.4, 0.03% Proclin 300
Stability & Storage	12 months from date of receipt / reconstitution, 2 to 8 °C as supplied.

Dilution

application	dilution	species
FCM	5μl per million cells in 100μl volume	Ms

Background

The CD3 protein is a T-cell marker, a complex of four structurally distinct membrane glycoprotein isoforms, 20-50 kDa, comprising extracellular, transmembrane and intracellular domains. CD3 is associated with an heterodimer creating the T-cell receptor (TCR). The CD3 complex is responsible for mediating signal transduction to the internal environment upon antigenic recognition by TCR, causing T-cell proliferation and release of cytokines.