S-RMab® Claudin18.2 Recombinant Rabbit mAb (SDT-102-83),specification,price,image-Bio-Equip in China

Product Detail
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Product Specification

Host	Rabbit
Antigen	Claudin18.2
Immunogen	Synthetic Peptide
Location	Membrane
Accession	P56856-2
Clone Number	SDT-102-83
Antibody Type	Rabbit mAb
Application	IHC-P
Reactivity	Hu, Ms, Rt
Purification	Protein A
Concentration	0.5 mg/ml
Physical Appearance	Liquid
Storage Buffer	PBS, 40% Glycerol, 0.05%BSA, 0.03% Proclin 300
Stability & Storage	12 months from date of receipt / reconstitution, -20 °C as supplied

Dilution

application	dilution	species
IHC-P	1:1000	null

Background

Claudin-18 is a protein that in humans is encoded by the CLDN18 gene. It belongs to the group of claudins. CLDN18 belongs to the large claudin family of proteins, which form tight junction strands in epithelial cells. Isoform 2 (Claudin 18.2) is abundant in gastric tumors. Claudin 18.2 is involved in tumor development and progression and located in the outer cell membrane. It has exposed extracellular loops and is available for monoclonal antibody binding.