EZH2 Recombinant Rabbit mAb(SDT-053-49),specification,price,image-Bio-Equip in China

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Product Specification

Host	Rabbit
Antigen	EZH2
Synonyms	ENX-1, Enhancer of zeste homolog 2, Lysine N-methyltransferase 6
Immunogen	Synthetic Peptide
Location	Nucleus, Intracellular
Accession	Q15910
Clone Number	SDT-053-49
Antibody Type	Rabbit mAb
Application	WB, IHC-P, ICC, IP, ICFCM
Reactivity	Hu, Ms, Rt
Predicted Reactivity	Mq
Purification	Protein A
Concentration	0.5mg/ml
Conjugation	Unconjugated
Physical Appearance	Liquid
Storage Buffer	PBS, 40% Glycerol, 0.05%BSA, 0.03% Proclin 300
Stability & Storage	12 months from date of receipt / reconstitution, -20 °C as supplied

Dilution

application	dilution	species
ICC	1:500
WB	1:5000
ICFCM	1:500
IHC-P	1:500
IP	1:50

Background

Enhancer of zeste homolog 2 (EZH2) is a histone-lysine N-methyltransferase enzyme (EC 2.1.1.43) encoded by EZH2 gene, that participates in histone methylation and, ultimately, transcriptional repression. EZH2 catalyzes the addition of methyl groups to histone H3 at lysine 27, by using the cofactor S-adenosyl-L-methionine. Methylation activity of EZH2 facilitates heterochromatin formation thereby silences gene function. Remodeling of chromosomal heterochromatin by EZH2 is also required during cell mitosis.