TCL1 Recombinant Rabbit mAb(SDT-052-12),specification,price,image-Bio-Equip in China

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Product Specification

Host	Rabbit
Antigen	TCL1
Synonyms	Oncogene TCL-1, Protein p14 TCL1
Immunogen	Synthetic Peptide
Location	Cytoplasm, Nucleus
Accession	P56279
Clone Number	SDT-052-12
Antibody Type	Rabbit mAb
Application	WB, IHC-P, IP
Reactivity	Hu
Purification	Protein A
Concentration	0.5mg/ml
Conjugation	Unconjugated
Physical Appearance	Liquid
Storage Buffer	PBS, 40% Glycerol, 0.05%BSA, 0.03% Proclin 300
Stability & Storage	12 months from date of receipt / reconstitution, -20 °C as supplied

Dilution

application	dilution	species
IHC-P	1:2000
WB	1:1000
IP	1:25

Background

T-cell leukemia/lymphoma protein 1A is a protein that in humans is encoded by the TCL1A gene. The TCL1 locus on human chromosome 14q32.1 is activated in T-cell leukemias by translocations and inversions that juxtapose it to regulatory elements of T-cell receptor genes. TCL1A has been shown to interact with AKT1 and AKT2. Protein expression in immature T and B lymphoid cells and overexpression of TCL1 is considered critical in the oncogenetic transformation.