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Collagen IV Recombinant Rabbit mAb (SDT-150-5)
Collagen IV Recombinant Rabbit mAb (SDT-150-5)
Origin of place Singapore
Model S0B3090-1mg
Supplier ANT BIO PTE.LTD.
Price 645
Hits 2
Updated 8/25/2025
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Product Specification


HostRabbit
AntigenCollagen IV
SynonymsCollagen type IV (CIV)
ImmunogenRecombinant Protein
LocationN/A
AccessionP02462
Clone NumberSDT-150-5
Antibody TypeRecombinant mAb
ApplicationSandwich ELISA
ReactivityHuman
PurificationProtein A
Concentration2 mg/ml
Purity>95% by HPLC
Physical AppearanceLiquid
Storage BufferPBS pH7.4, 0.03% Proclin 300
Stability & Storage

12 months from date of receipt / reconstitution, 2 to 8 °C as supplied.

Background

Type IV collagen is a type of collagen that is responsible for providing a scaffold for stability and assembly. It is also predominantly found in extracellular basement membranes. It aids in cell adhesion, migration, survival, expansion, and differentiation. After secretion into the extracellular membrane, these molecules will further interact to form higher molecular organizations. These, along with other proteins, will form unique basement membranes in tissue-specific manners. Through interactions with specific cellular receptors such as integrins, the basement membrane collagen IV networks not only provide structural support to the cells and tissues, but they also affect the biological rate during and after the development. New discoveries keep unraveling information about genetic mutations, biosynthesis, molecular assembly, and network formation of type IV collagen, and this increases the understanding of the critical role of this collagen in health and disease.Liver fibrosis and cirrhosis are associated with the deposition of collagen IV in the liver. Serum Collagen IV concentrations correlate with hepatic tissue levels of collagen IV in subjects with alcoholic liver disease and hepatitis C and fall following successful therapy.

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