The AUTOBIO antibody to hepatitis B surface antigen (Anti-HBs) chemiluminescence immunoassay (CLIA) is intended for the quantitative determination of Anti-HBs concentration in human serum and plasma.

Anti-HBs titer can be determined to monitor the prognosis of patients recovering from the hepatitis B viral infection. It also can be used as an indicator of prior exposure to Hepatitis B viruses. However, it is an immune response index for people who received HBV vaccine.

The antibody response to hepatitis B virus surface antigen (anti-HBs) is an important serological marker for vaccine induced immunity to hepatitis B virus (HBV). An adequate vaccine response is defined as an anti-HBs level of higher than 100IU/l 4 to 8 weeks after the last of three or four vaccine injections. It is widely accepted that a sustained level of at least 10IU/l is protective against HBV infection. Vaccinees withoutsufficient anti-HBs responses, so-called nonresponders or low responders, undergo a special regimen of additional vaccine doses. For liver transplant recipients, quantitative measurement of anti-HBs levels is used in the management of hepatitis B immune globulin prophylaxis, which is initiated to maintain anti-HBs levels of at least 100IU/l or 200IU/l, according to different guidelines.

These are divided into four categories based on Anti-HBs concentration
(I)   nonresponders: less than 1mIU/ml
(II)  low responders: 1-10mIU/ml
(III) Medium responders: 10-100mIU/ml
(IV) High responders: more than 100mIU/ml

About Group
Autobio is located at Zhengzhou, China and made up of Autobio Co., Ltd and Autobio Diagnostics Co., Ltd., which are all specialized in the field of providing solutions for clinical immunological diagnosis.

With GMP certified facilities and experienced staffs, we have developed high-quality in vitro diagnostic reagents with the competitive price.

In 2007 Autobio Labtec Instruments Co.Ltd. was founded, adding instrumentation to the product portfolio of the Autobio group. A close cooperation with an experienced R&D team in Europe and a highly qualified team in charge of production enables Autobio Labtec instruments to offer state of the art instrumentation to the domestic and international market.

Autobio Co. Ltd.
.. was established in 1998, as a company focusing on the sales and marketing of the range of diagnostic products developed and manufactured within Autobio group.

Autobio Diagnostics Co. Ltd.
... was established in 1999, and has become one of the largest and fastest growing clinical diagnostic companies in China. We are specialized in research & development, production and distribution of clinical diagnostic products which mainly focused on CLIA, ELISA, microbiology and Rapid Test Strips/devices.