TNNC2 (Troponin C2, Fast Skeletal Type) is a Protein Coding gene. Diseases associated with TNNC2 include Distal Arthrogryposis. Among its related pathways are Calcium signaling pathway and Striated Muscle Contraction. Troponin (Tn), a key protein complex in the regulation of striated muscle contraction, is composed of 3 subunits. The Tn-I subunit inhibits actomyosin ATPase, the Tn-T subunit binds tropomyosin and Tn-C, while the Tn-C subunit binds calcium and overcomes the inhibitory action of the troponin complex on actin filaments. The protein encoded by TNNC2 is the Tn-C subunit.

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000 ELISA 1:5000-20000.

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