The protein encoded by IL36A is a cytokine that can activate NF-kappa-B and MAPK signaling pathways to generate an inflammatory response. The encoded protein functions primarily in skin and demonstrates increased expression in psoriasis. In addition, decreased expression of IL36A has been linked to a poor prognosis in both hepatocellular carcinoma and colorectal cancer patients. IL36A (Interleukin 36, Alpha) is a Protein Coding gene. Diseases associated with IL36A include Psoriasis. Among its related pathways are Toll-Like receptor Signaling Pathways and Cytokine Signaling in Immune system.

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC-p 1:50-200, ELISA 1:10000-20000.

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Abbkine Scientific Co., Ltd. was founded by a number of scientists and marketing experts in the field of life science in California in 2012. With growing demands from Asia Pacific, it move its headquarters to China. Combining cutting edge technology from United States with China's manufacturing engineering and cost advantages, we aim to provide innovative, high quality assay kits, recombinant proteins, antibodies and other research tools to accelerate life science fundamental research, drug discovery, etc.