INSL3 encodes a member of the insulin-like hormone superfamily. The encoded protein is mainly produced in gonadal tissues. Studies of the mouse counterpart suggest that INSL3 may be involved in the development of urogenital tract and female fertility. This protein may also act as a hormone to regulate growth and differentiation of gubernaculum, and thus mediating intra-abdominal testicular descent. Mutations in INSL3 may lead to cryptorchidism. Alternate splicing results in multiple transcript variants. INSL3 (Insulin Like 3) is a Protein Coding gene. Diseases associated with INSL3 include Cryptorchidism and Testicular Cancer. Among its related pathways are G alpha (s) signalling events and Signaling by GPCR.

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC-p 1:50-200, ELISA 1:10000-20000.

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Abbkine Scientific Co., Ltd. was founded by a number of scientists and marketing experts in the field of life science in California in 2012. With growing demands from Asia Pacific, it move its headquarters to China. Combining cutting edge technology from United States with China's manufacturing engineering and cost advantages, we aim to provide innovative, high quality assay kits, recombinant proteins, antibodies and other research tools to accelerate life science fundamental research, drug discovery, etc.