Parathyroid hormone receptor 2 is a protein encoded by this gene is a member of the G-protein coupled receptor family 2. This protein is a receptor for parathyroid hormone (PTH). This receptor is more selective in ligand recognition and has a more specific tissue distribution compared to parathyroid hormone receptor 1 (PTHR1). There is 30 to 70% amino acid sequence identity between receptors within the secretin receptor family, but these receptors have essentially no sequence identity with most known G protein-coupled receptors of the rhodopsin family or with the metabotropic glutamate receptor family. PTHR2 is most similar (51% overall amino acid identity) to the PTH/PTHRP receptor. The PTHR2 gene was most abundantly expressed in brain, pancreas, testis, and placenta.
Human Parathyroid hormone 2 receptor (PTH2R) ELISA Kit employs a two-site sandwich ELISA to quantitate PTH2R in samples. An antibody specific for PTH2R has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and anyPTH2R present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for PTH2R is added to the wells. After washing, Streptavidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of PTH2R bound in the initial step. The color development is stopped and the intensity of the color is measured.
Human Parathyroid hormone 2 receptor (PTH2R) ELISA Kit listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Find more details at http://www.abbkine.com/product/human-parathyroid-hormone-2-receptor-pth2r-elisa-kit-kte61064/
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