The deduced 469-amino acid protein has the characteristic 7-transmembrane domain structure of a G protein-coupled receptor, as well as 2 putative N-glycosylation sites in its N-terminal domain. SALPR shares highest sequence similarity with somatostatin receptors and angiotensin receptors. SALPR expression was not detected by Northern blot analysis. RT-PCR detected SALPR expression predominantly in brain, with highest expression in substantia nigra and pituitary, followed by hippocampus, spinal cord, amygdala, caudate nucleus, and corpus callosum; expression was very low in cerebellum. In peripheral tissues, relatively high expression was detected in adrenal gland, and low expression was detected in pancreas, salivary gland, placenta, mammary gland, and testis. Little to no expression was detected in other tissues examined.

Human Relaxin-3 receptor 1 (RXFP3) ELISA Kit employs a two-site sandwich ELISA to quantitate RXFP3 in samples. An antibody specific for RXFP3 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and anyRXFP3 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for RXFP3 is added to the wells. After washing, Streptavidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of RXFP3 bound in the initial step. The color development is stopped and the intensity of the color is measured.

Human Relaxin-3 receptor 1 (RXFP3) ELISA Kit listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

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Abbkine Scientific Co., Ltd. was founded by a number of scientists and marketing experts in the field of life science in California in 2012. With growing demands from Asia Pacific, it move its headquarters to China. Combining cutting edge technology from United States with China's manufacturing engineering and cost advantages, we aim to provide innovative, high quality assay kits, recombinant proteins, antibodies and other research tools to accelerate life science fundamental research, drug discovery, etc.