Amino acid transporters play essential roles in the uptake of nutrients, production of energy, chemical metabolism, detoxification, and neurotransmitter cycling. SLC38A1 is an important transporter of glutamine, an intermediate in the detoxification of ammonia and the production of urea. Glutamine serves as a precursor for the synaptic transmitter, glutamate.The deduced 487-amino acid protein is predicted to have a cytoplasmic N terminus followed by 11 putative transmembrane domains and an extracellular C terminus. ATA1 has 2 N-glycosylation sites in the putative extracellular loop between transmembrane domains 5 and 6, and several protein kinase C phosphorylation sites. ATA1 shares 93% identity with rat Ata1 and 52% identity with human ATA2 (SLC38A2).

Human Sodium-coupled neutral amino acid transporter 1 (SLC38A1) ELISA Kit employs a two-site sandwich ELISA to quantitate SLC38A1 in samples. An antibody specific for SLC38A1 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and anySLC38A1 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for SLC38A1 is added to the wells. After washing, Streptavidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of SLC38A1 bound in the initial step. The color development is stopped and the intensity of the color is measured.

Human Sodium-coupled neutral amino acid transporter 1 (SLC38A1) ELISA Kit listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

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Abbkine Scientific Co., Ltd. was founded by a number of scientists and marketing experts in the field of life science in California in 2012. With growing demands from Asia Pacific, it move its headquarters to China. Combining cutting edge technology from United States with China's manufacturing engineering and cost advantages, we aim to provide innovative, high quality assay kits, recombinant proteins, antibodies and other research tools to accelerate life science fundamental research, drug discovery, etc.