Spatacsin (SPG11) is a potential transmembrane protein that is phosphorylated upon DNA damage. Defects in this gene are a cause of spastic paraplegia type 11 (SPG11). Multiple transcript variants encoding different isoforms have been found for this gene.

Human Spatacsin (SPG11) ELISA Kit employs a two-site sandwich ELISA to quantitate SPG11 in samples. An antibody specific for SPG11 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and anySPG11 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for SPG11 is added to the wells. After washing, Streptavidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of SPG11 bound in the initial step. The color development is stopped and the intensity of the color is measured.

Human Spatacsin (SPG11) ELISA Kit listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Find more details at http://www.abbkine.com/product/human-spatacsin-spg11-elisa-kit-kte60535/

Abbkine Scientific Co., Ltd. was founded by a number of scientists and marketing experts in the field of life science in California in 2012. With growing demands from Asia Pacific, it move its headquarters to China. Combining cutting edge technology from United States with China's manufacturing engineering and cost advantages, we aim to provide innovative, high quality assay kits, recombinant proteins, antibodies and other research tools to accelerate life science fundamental research, drug discovery, etc.