P2Y purinoceptor 14 is a protein belongs to the family of G-protein coupled receptors, which contains several receptor subtypes with different pharmacological selectivity for various adenosine and uridine nucleotides.This receptor is a P2Y purinergic receptor for UDP-glucose and other UDP-sugars coupled to G-proteins. It has been implicated in extending the known immune system functions of P2Y receptors by participating in the regulation of the stem cell compartment, and it may also play a role in neuroimmune function. Two transcript variants encoding the same protein have been identified for this gene.The predicted 338-amino acid protein contains transmembrane domains and a tyrosine kinase phosphorylation site.

Rat P2Y purinoceptor 14 (P2RY14) ELISA Kit employs a two-site sandwich ELISA to quantitate P2RY14 in samples. An antibody specific for P2RY14 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and anyP2RY14 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for P2RY14 is added to the wells. After washing, Streptavidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of P2RY14 bound in the initial step. The color development is stopped and the intensity of the color is measured.

Rat P2Y purinoceptor 14 (P2RY14) ELISA Kit listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

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