Protein tyrosine phosphatase type IVA 1 is an enzyme belongs to a small class of prenylated protein tyrosine phosphatases (PTPs), which contains a PTP domain and a characteristic C-terminal prenylation motif. PTPs are cell signaling molecules that play regulatory roles in a variety of cellular processes. This tyrosine phosphatase is a nuclear protein, but may primarily associate with plasma membrane.The surface membrane association of this protein depends on its C-terminal prenylation. Overexpression of this gene in mammalian cells conferred a transformed phenotype, which implicated its role in the tumorigenesis. Studies in rat suggested that this gene may be an immediate-early gene in mitogen-stimulated cells.

Rat Protein tyrosine phosphatase type IVA 1 (PTP4A1) ELISA Kit employs a two-site sandwich ELISA to quantitate PTP4A1 in samples. An antibody specific for PTP4A1 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and anyPTP4A1 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for PTP4A1 is added to the wells. After washing, Streptavidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of PTP4A1 bound in the initial step. The color development is stopped and the intensity of the color is measured.

Rat Protein tyrosine phosphatase type IVA 1 (PTP4A1) ELISA Kit listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

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