Regenerating islet-derived protein 3 alpha is a pancreatic secretory protein that may be involved in cell proliferation or differentiation. It has similarity to the C-type lectin superfamily. The enhanced expression of this gene is observed during pancreatic inflammation and liver carcinogenesis. The predicted protein had the same size as the rat protein and showed 71% amino acid identity, the 6 half-cysteines being in identical positions. As in the rat, the protein was expressed at very low levels in control tissues and overexpressed during the acute phase of pancreatitis in humans. The protein could be immunolocalized to the apical regions of acinar cells. The protein was also quantifiable in serum with an elevation of levels in pancreatitis, suggesting its possible use as a biologic marker of the disease.

Rat Regenerating islet-derived protein 3-alpha (REG3A) ELISA Kit employs a two-site sandwich ELISA to quantitate REG3A in samples. An antibody specific for REG3A has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and anyREG3A present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for REG3A is added to the wells. After washing, Streptavidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of REG3A bound in the initial step. The color development is stopped and the intensity of the color is measured.

Rat Regenerating islet-derived protein 3-alpha (REG3A) ELISA Kit listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

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Abbkine Scientific Co., Ltd. was founded by a number of scientists and marketing experts in the field of life science in California in 2012. With growing demands from Asia Pacific, it move its headquarters to China. Combining cutting edge technology from United States with China's manufacturing engineering and cost advantages, we aim to provide innovative, high quality assay kits, recombinant proteins, antibodies and other research tools to accelerate life science fundamental research, drug discovery, etc.