Fatty acid binding protein 7, brain (FABP7; also brain lipid binding protein, BLBP), is a brain fatty acid binding protein. Fatty acid binding proteins (FABPs) are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. FABPs are thought to play roles in fatty acid uptake, transport, and metabolism.FABP7 is expressed, during development, in radial glia by the activation of Notch receptors. Reelin was shown to induce FABP7 expression in neural progenitor cells via Notch-1 activation. According to one study, FABP7 binds DHA with the highest affinity among all of the FABPs.FABP7 maps onto human chromosome 6q22.31, a schizophrenia linkage region corroborated by a meta-analysis..

Mouse Fatty acid-binding protein, brain (FABP7) ELISA Kit employs a two-site sandwich ELISA to quantitate FABP7 in samples. An antibody specific for FABP7 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and anyFABP7 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for FABP7 is added to the wells. After washing, Streptavidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of FABP7 bound in the initial step. The color development is stopped and the intensity of the color is measured.

Mouse Fatty acid-binding protein, brain (FABP7) ELISA Kit listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

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