Vertebrate DM domain genes encode a novel group of proteins related to the Drosophila doublesex and Caenorhabditis elegans mab-3 transcription factors. It is shown here that the recently identified gene, DMRT3, has a restricted embryonic expression profile that is conserved in chicken and mouse embryos. DMRT3 is expressed primarily in the forebrain, neural tube and nasal placode of both species. In the chicken, DMRT3 is also expressed in newly forming tail somites at early developmental stages and, later, in the Müllerian ducts of the urogenital system.The sequence of this gene is defined by 14 GenBank accessions from 13 cDNA clones, some from colon, PCR rescued clones (seen 2 times), thalamus (2), colon (once), colon tumor RER+ (once), lung (once), parathyroid gland (once), parathyroid tumor (once) and 4 other tissues.

Mouse Doublesex- and mab-3-related transcription factor 3 (DMRT3) ELISA Kit employs a two-site sandwich ELISA to quantitate DMRT3 in samples. An antibody specific for DMRT3 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and anyDMRT3 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for DMRT3 is added to the wells. After washing, Streptavidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of DMRT3 bound in the initial step. The color development is stopped and the intensity of the color is measured.

Mouse Doublesex- and mab-3-related transcription factor 3 (DMRT3) ELISA Kit listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Find more details at http://www.abbkine.com/product/mouse-doublesex-and-mab-3-related-transcription-factor-3-dmrt3-elisa-kit-kte71241/

Abbkine Scientific Co., Ltd. was founded by a number of scientists and marketing experts in the field of life science in California in 2012. With growing demands from Asia Pacific, it move its headquarters to China. Combining cutting edge technology from United States with China's manufacturing engineering and cost advantages, we aim to provide innovative, high quality assay kits, recombinant proteins, antibodies and other research tools to accelerate life science fundamental research, drug discovery, etc.