Galectin-8 is one of the galectins, beta-galactoside-binding lectins with conserved carbohydrate recognition domains (CRD). Galectin-8 essentially consists of two carbohydrate recognition domains separated by a linker that bears no similarity to any known protein. The gene symbol is LGALS8 . Galectin-8 has been identified originally as PCTA1 [Prostate carcinoma tumor antigen 1], an antigen expressed by prostate cancer cells .Several isoforms appear to be expressed differentially in various tumoral cells . The protein is identical with Po66-CBP [Po66 carbohydrate-binding protein], identified by the Po66 monoclonal antibody.

Mouse Galectin-8 (LGALS8) ELISA Kit employs a two-site sandwich ELISA to quantitate LGALS8 in samples. An antibody specific for LGALS8 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and anyLGALS8 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for LGALS8 is added to the wells. After washing, Streptavidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of LGALS8 bound in the initial step. The color development is stopped and the intensity of the color is measured.

Mouse Galectin-8 (LGALS8) ELISA Kit listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

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