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Home >Products> Reagents >ELISA / Diagnostic Kits> Human Soluble transferrin receptor (sTfR) ELISA Kit
Human Soluble transferrin receptor (sTfR) ELISA Kit
Human Soluble transferrin receptor (sTfR) ELISA Kit
Origin of place China
Model KTE62630
Supplier Abbkine Scientific
Price
Hits 173
Updated 10/16/2019
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Transferrin receptor  is a carrier protein for transferrin. It is needed for the import of iron into the cell and is regulated in response to intracellular iron concentration. Low iron concentrations promote increased levels of transferrin receptor, to increase iron intake into the cell. Thus, transferrin receptor maintains cellular iron homeostasis. Expression of human TFR1, but not human TFR2, in hamster cell lines markedly enhanced the infection of viruses pseudotyped with the glycoprotein of Machupo, Guanarito, and Junin viruses, but not with those of Lassa or lymphocytic choriomeningitis viruses. An anti-TFR1 antibody efficiently inhibited the replication of Machupo, Guanarito, Junin, and Sabia viruses, but not that of Lassa virus.TFR1 is a cellular receptor for New World hemorrhagic fever arenaviruses.

Human Soluble transferrin receptor (sTfR) ELISA Kit employs a two-site sandwich ELISA to quantitate sTfR in samples. An antibody specific for sTfR has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and anysTfR present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for sTfR is added to the wells. After washing, Streptavidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of sTfR bound in the initial step. The color development is stopped and the intensity of the color is measured.

Human Soluble transferrin receptor (sTfR) ELISA Kit listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Find more details at http://www.abbkine.com/product/human-soluble-transferrin-receptor-stfr-elisa-kit-kte62630/

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