CLIM1 and CLIM2 have a very high level of identity to each other and to the homologs in other species.CLIM2 encodes a 375-amino acid protein.human LMO2 interacted with human BEX2. Electrophoretic mobility shift assays showed that BEX2 and LMO2 were part of a DNA-binding complex that recognized the E-box element. Other components of this complex included NSCL2 (NHLH2) and LDB1. LDB1 associated with a complex containing LMO4, CTIP, and BRCA1 in transfected human embryonic kidney cells.LDB1 was consistently enriched in the superior temporal gyrus posterior temporal cortex, and perisylvian cortex. LDB1 may be involved in asymmetric patterning of the developing human cortex.

Human LIM domain-binding protein 1 (LDB1) ELISA Kit employs a two-site sandwich ELISA to quantitate LDB1 in samples. An antibody specific for LDB1 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and anyLDB1 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for LDB1 is added to the wells. After washing, Streptavidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of LDB1 bound in the initial step. The color development is stopped and the intensity of the color is measured.

Human LIM domain-binding protein 1 (LDB1) ELISA Kit listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

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Abbkine Scientific Co., Ltd. was founded by a number of scientists and marketing experts in the field of life science in California in 2012. With growing demands from Asia Pacific, it move its headquarters to China. Combining cutting edge technology from United States with China's manufacturing engineering and cost advantages, we aim to provide innovative, high quality assay kits, recombinant proteins, antibodies and other research tools to accelerate life science fundamental research, drug discovery, etc.