Leukocyte immunoglobulin-like receptor subfamily B member 4is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs).The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. The receptor can also function in antigen capture and presentation. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity.

Human Leukocyte immunoglobulin-like receptor subfamily B member 5 (LILRB5) ELISA Kit employs a two-site sandwich ELISA to quantitate LILRB5 in samples. An antibody specific for LILRB5 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and anyLILRB5 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for LILRB5 is added to the wells. After washing, Streptavidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of LILRB5 bound in the initial step. The color development is stopped and the intensity of the color is measured.

Human Leukocyte immunoglobulin-like receptor subfamily B member 5 (LILRB5) ELISA Kit listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

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