Membrane palmitoylated protein 7 encoded by MPP7 is a member of the p55 Stardust family of membrane-associated guanylate kinase (MAGUK) proteins, which function in the establishment of epithelial cell polarity. This family member forms a complex with the polarity protein DLG1 (discs, large homolog 1) and facilitates epithelial cell polarity and tight junction formation. Polymorphisms in MPP7 are associated with variations in site-specific bone mineral density (BMD). Alternative splicing results in multiple transcript variants.

Human MAGUK p55 subfamily member 7 (MPP7) ELISA Kit employs a two-site sandwich ELISA to quantitate MPP7 in samples. An antibody specific for MPP7 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and anyMPP7 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for MPP7 is added to the wells. After washing, Streptavidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of MPP7 bound in the initial step. The color development is stopped and the intensity of the color is measured.

Human MAGUK p55 subfamily member 7 (MPP7) ELISA Kit listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

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