NARS2 encodes a putative member of the class II family of aminoacyl-tRNA synthetases. These enzymes play a critical role in protein biosynthesis by charging tRNAs with their cognate amino acids. This protein is encoded by the nuclear genome but is likely to be imported to the mitochondrion where it is thought to catalyze the ligation of asparagine to tRNA molecules. Mutations in NARS2 have been associated with combined oxidative phosphorylation deficiency 24 (COXPD24).

Human Probable asparaginyl-tRNA synthetase, mitochondrial (NARS2) ELISA Kit employs a two-site sandwich ELISA to quantitate NARS2 in samples. An antibody specific for NARS2 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and anyNARS2 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for NARS2 is added to the wells. After washing, Streptavidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of NARS2 bound in the initial step. The color development is stopped and the intensity of the color is measured.

Human Probable asparaginyl-tRNA synthetase, mitochondrial (NARS2) ELISA Kit listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

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Abbkine Scientific Co., Ltd. was founded by a number of scientists and marketing experts in the field of life science in California in 2012. With growing demands from Asia Pacific, it move its headquarters to China. Combining cutting edge technology from United States with China's manufacturing engineering and cost advantages, we aim to provide innovative, high quality assay kits, recombinant proteins, antibodies and other research tools to accelerate life science fundamental research, drug discovery, etc.