It has an N-terminal coiled-coil region that shares 45% amino acid identity with an N-terminal region in AKAP2 . Overall, PALML shares 36% amino acid identity with paralemmin (PALM). The shorter PALML variant encodes a deduced 471-amino acid protein that, compared with long isoform, lacks the N-terminal coiled-coil region and differs in the first 19 amino acids. Northern blot analysis detected a 2.4-kb PALML transcript enriched in testis, prostate, heart, and skeletal muscle. No expression was detected in brain and peripheral blood leukocytes, and alternative transcripts were detected in heart, liver, and skeletal muscle. Epitope-tagged PALML was expressed throughout the cytoplasm of transfected COS-7 cells and was excluded from the nucleus.

Human Palmdelphin (PALMD) ELISA Kit employs a two-site sandwich ELISA to quantitate PALMD in samples. An antibody specific for PALMD has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and anyPALMD present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for PALMD is added to the wells. After washing, Streptavidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of PALMD bound in the initial step. The color development is stopped and the intensity of the color is measured.

Human Palmdelphin (PALMD) ELISA Kit listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

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Abbkine Scientific Co., Ltd. was founded by a number of scientists and marketing experts in the field of life science in California in 2012. With growing demands from Asia Pacific, it move its headquarters to China. Combining cutting edge technology from United States with China's manufacturing engineering and cost advantages, we aim to provide innovative, high quality assay kits, recombinant proteins, antibodies and other research tools to accelerate life science fundamental research, drug discovery, etc.