PLUNC is the human homolog of murine plunc, and like the mouse gene, is specifically expressed in the upper airways and nasopharyngeal regions. The exact biological function of this gene is not known, however, it has been suggested to be involved in inflammatory responses to irritants in the upper airways. It may also serve as a potential molecular marker for detection of micrometastasis in non-small-cell lung cancer. Multiple transcript variants resulting from alternative splicing in the 3' UTR have been detected, but the full-length nature of only two is known.The cDNA encodes a leucine-rich protein of 256 amino acids that is 72% identical to the murine protein. within the human PLUNC family, amino acid sequence identity is low, ranging from 16 to 28%.

Human Lung specific X protein (LUNX) ELISA Kit employs a two-site sandwich ELISA to quantitate PLUNC in samples. An antibody specific for PLUNC has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and anyPLUNC present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for PLUNC is added to the wells. After washing, Streptavidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of PLUNC bound in the initial step. The color development is stopped and the intensity of the color is measured.

Human Lung specific X protein (LUNX) ELISA Kit listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

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Abbkine Scientific Co., Ltd. was founded by a number of scientists and marketing experts in the field of life science in California in 2012. With growing demands from Asia Pacific, it move its headquarters to China. Combining cutting edge technology from United States with China's manufacturing engineering and cost advantages, we aim to provide innovative, high quality assay kits, recombinant proteins, antibodies and other research tools to accelerate life science fundamental research, drug discovery, etc.