M-CSF (macrophage colony stimulating factor, colony stimulating factor 1, CSF-1) is a hemtopoietic growth factor produced by monocytes, granulocytes, endothelial cells, fibroblasts and activated B-cells and T-cells. M-CSF stimulates macrophage colony formation and regulates proliferation and differentiation of hematopoeitic stem cells into macrophages and regulates survival and differentiation of monocytes. It enhances antibody-dependent cell-mediated cytotoxity, enhances marophage killing of tumor cells and microorganisms, regulates the release of cytokines and inhibits bone resorption by osteoclasts. Human M-CSF shows biological ativity on murine and rat cells and although murine M-CSF is active in rat cells it is inactive in human cells.
ISOkine™ recombinant M-CSF is produced in the endosperm tissue of barley grain (Hordeum vulgare), that exhibits up to 50 times less protease activity than E.coli or mammalian cells. Barley seed is void of any human or animal viral contaminants that could jeopardize your cell culture. Hordeum vulgare is an endotoxin free source, eliminating the risk of trace endotoxin harming your cell culture.
Purity greater than 95% by SDS-PAGE gel analysis.
bio-equip.cn
ORF Genetics is a pioneer in the manufacturing of growth factors and other recombinant proteins in plants. The company’s ISOkine? human-like growth factors are produced in the company’s proprietary Orfeus? system in barley, bypassing the use of bacterial or animal cell systems.We promise unprecedented purity of our products.
The company is offering its unique ISOkine? growth factors for various medical research, cell culture media and diagnostics.
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