Flt3-ligand (FMS related tyrosine kinase 3 ligand, flk-2 ligand) is involved in proliferation and differentiation of early hematopietic cells. Flt3-ligand synergizes with other CSF’s and interleukins to induce proliferation of early hematopoietic cells, but does not stimulate growth or differentation alone. Flt3-ligand binds to cells expressing the tyrosine kinase receptor Flt3.

ISOkine™ recombinant Flt3-ligand is produced in the endosperm tissue of barley grain (Hordeum vulgare), that exhibits up to 50 times less protease activity than E.coli or mammalian cells. Barley seed is void of any human or animal viral contaminants that could jeopardize your cell culture. Hordeum vulgare is an endotoxin free source, eliminating the risk of trace endotoxin harming your cell culture.

Purity greater than 95% by SDS-PAGE gel analysis.

ORF Genetics is a pioneer in the manufacturing of growth factors and other recombinant proteins in plants. The company’s ISOkine? human-like growth factors are produced in the company’s proprietary Orfeus? system in barley, bypassing the use of bacterial or animal cell systems.We promise unprecedented purity of our products.
The company is offering its unique ISOkine? growth factors for various medical research, cell culture media and diagnostics.