SG-BSV reproducible microsphere reaction vessel
SG-BSV series reproducible microsphere reaction vessel 1ml&SG-BSV0001
The revolutionary advantage of SG-BSV series spherical geometric structure cultivation container in dynamic 3D cultivation
Breakthrough in geometric dimensions, cell culture moves from plane to solid
In the field of cell culture, the two-dimensional environment constructed by traditional culture bottles and dishes is no longer sufficient to meet the depth requirements of modern life science research. SAGE-BIO's innovative spherical geometric structure culture container achieves a revolutionary upgrade of the cellular microenvironment through three-dimensional spatial reconstruction.
 
SG-BSV 1ml reproducible microsphere reaction vessel
The value of SG-BSV micro sphere reaction vessel
In response to the demand for micro experiments such as stem cell research and organoid culture, the SG-BSV series 1ml/2ml/4ml/10ml reproducible micro sphere reaction containers developed by Sage Biotech demonstrate four major application directions and innovative breakthroughs based on the advantages of large container technology:
1. Research on stem cell fate regulation
Single cell spheroidization analysis: A 1ml container supports spheroidization experiments with single-cell resolution, revealing the self-renewal and differentiation trajectories of stem cells;
Gene editing microenvironment: Low volume system reduces off target effects of CRISPR and improves editing efficiency;
Optimization of serum-free culture: The spherical structure enhances cell-cell contact, and the success rate of serum-free medium adaptation is significantly improved;
2. Modeling of organoid function
Tumor organoid drug sensitivity testing: 4ml container supports PDX model construction and can be used for chemotherapy drug response prediction research;
Research on the Development of Neurological Organs: Dynamic Fluid Induced Synaptic Network Formation;
Simulation of hepatic organ metabolism: research on drug metabolism accelerated by hypergravity environment;
3. Microgravity biology research
Aerospace medicine pre research: DARC-G platform simulates microgravity environment in space to study the effect of weightlessness on bone cell differentiation;
Development of tissue engineering scaffolds: enhanced nutrient infiltration in a hypergravity environment, and increased cell infiltration rate in three-dimensional scaffolds;
Protein crystal growth: Micro shear environment supports high-quality crystal cultivation, increasing the success rate of structural analysis;
4. Rare cell isolation and expansion, such as capturing circulating tumor cells, can enhance CTC aggregation effect in spherical structure culture containers, and the capture efficiency is expected to be improved compared to flat culture;
 
Characteristics of the SG-BSV sphere reaction vessel of Saiji Biotechnology
Saiji Biotechnology has innovatively proposed a new solution in the field of new biological reaction vessels through the collaborative innovation of the three elements of geometry fluid biology
1. Fluid dynamics optimization design: Computational fluid dynamics (CFD) simulation is used to design the internal structure of the container, ensuring that each sphere receives uniform nutrient supply and mechanical stimulation;
2. Breakthrough in Materials Science: Ultra low adhesion surface treatment supports up to 30 days of unsupported sphere cultivation. Medical grade polyetheretherketone (PEEK), PC and other materials can withstand high temperature sterilization at 121 ℃ and can be reused, saving daily use costs;
3. Symmetrical dual gas exchange membranes ensure sufficient gas exchange inside and outside the spherical container;
4. Ecological solution: From 1ml micro research to 1350ml, the entire series of containers share a unified technology platform. Modular design supports user-defined adapters and can load more than 20 high-throughput applications at once;
5. The convenient bubble discharge scheme can quickly construct a culture environment that is 100% filled with culture medium, avoiding turbulence or local shear force increase caused by irregular disturbance of bubbles in three-dimensional dynamic motion.
 
Sage Biotech SG-BSV redefines cell culture methods
The launch of the SG-BSV sphere reaction vessel series by Saiji Biotechnology not only marks the leap of cell culture technology from the "flat era" to the "three-dimensional era", but also creates a new solution for the integration of micro research and industrial production. By simulating the geometric reconstruction of physiological environments, controllable mechanical stimuli, and intelligent monitoring systems, these innovative culture containers will undoubtedly open up a new dimension of "decoding cellular physiological behavior" for global researchers. Widely applied in cutting-edge fields such as regenerative medicine, precision medicine, and space biology.
Please call+86 0 13862149980 for detailed information.

SUZHOU SAGE-BIO TECHNOLOCY CO.,LTD. is an innovative technology company specializing in the field of cell culture. The company's vision is to promote cell applications and assisted reproduction through innovation, benefiting the public. The main initiators of the company have many years of work experience in the life sciences and medical equipment industries, and are familiar with the mainstream cell culture technologies in the current market, as well as cutting-edge technologies and products applied to cell 3D culture, dynamic culture, mechanical culture, etc. Especially in the fields of training program design, automatic control structure, and silicone material application, he has rich experience. As of 2023, Saiji Biotechnology has successfully launched DARC series microgravity simulation culture system, SARC series rotating cell culture system, RSED series rotating embryo culture system, as well as COCS multi-stage co culture, perfusion culture, MSCS in vitro dynamic large-scale expansion culture and other products to the market. The product covers many application scenarios such as dynamic 3D cell culture, dynamic adherent culture, dynamic suspension culture, microgravity or supergravity simulation culture, pressure culture, anaerobic culture, as well as embryo and organoid culture.

In addition to selling standard products, SAGE-BIO can also provide customized products and services based on user needs. These include the entire process from requirements to solutions, from solutions to products, and from products to applications. At present, SAGE-BIO has successfully provided customized products for some users, which are applied in cell culture, embryo culture, organoid culture, as well as microgravity, supergravity simulation and other fields. The product involves multiple fields such as life sciences and new energy research, and has been recognized by users.