Creative Biolabs offers assay services of evaluating the stability of TCR/CD3 complex to ensure the harvest of high quality TCR-modified T cells. The effective interaction of CD3 with TCR and the ξ-chain is required for the generation of activation signal in T lymphocytes. Increased stability of the TCR/CD3complex contributes to the enhanced antitumor response activity of T cells. At Creative Biolabs, the TCR/CD3 complex stability assay can be achieved via immunoprecipitation and immunoblot. Creative Biolabs offers assay services to evaluate the stability of TCR/CD3 and ensure obtain high quality TCR-modified T cells.
https://www.creative-biolabs.com/car-t/tcr-cd3-stability-assay.htm
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Creative Biolabs is the leading custom service provider that has extensive experience in various antibody production and engineering fields. Our service portfolio includes mouse and rat monoclonal antibody production using hybridoma technology, human, monkey, rabbit,chicken, dog, llama and camel monoclonal antibody production using various antibody library technologies [including phage display, bacterial display and yeast display]. We are also professional in conducting in depth antibody humanization and affinity maturation usingphage display and DNA mutagenesis approaches. In addition, OEM services for bulk scale antibody manufacturing, including bacterial production of scFv, diabody, tandem scFv, miniantibody and Fab, and mammalian cell expression of minibody, chimeric IgG and IgG, are also available at the most competitive price in the industry.