The ROS1 proto-oncogene encodes a protein with tyrosine kinase activity. This protein is highly expressed in several tumor types. The protein may function as a growth or differentiation factor receptor. Chromosomal rearrangements involving the ROS1 gene were originally described in glioblastomas. More recently, ROS1 rearrangements have been identified as a potential "driver" mutation in non-small cell lung cancer and cholangiocarcinoma. 

Empire Genomics has developed a custom ROS1 probe which can be used to detect/confirm a rearrangement of the ROS1 gene. The probe comes labeled in orange, and generally ships within 24 hours. You can choose to customize the probe to meet your needs, which will ship right after production of the probe is complete (approximately 1 week).

Probe Details

Gene:	ROS1 (Orange 5-TAMRA dUTP)
Loci:	6q22
Test Kits:	20

The leading supplier of molecular diagnostics for customization and production of FISH probes, aGCH assays and upcoming new technologies to be used by Reference labs, Academic labs, Pharma, CRO’s
and Pharma /Biotech companies around the world.

Our companion Diagnostics will allow you to :
-Validate Bio-markers (signature identification and resistance).
-Identify and qualify the aberration at the Chromosomal level of specific population.
-Follow up the result of therapeutic treatment (monitoring, compound profiling, drug response, patient stratification and safety)
-Compare with the result of your current technology.
-Be translated into the initial phase of your diagnostics development toward new FDA filings (pre-clinical through clinical trial development).