The RET proto-oncogene codes for a tyrosine kinase. Mutations of the RET gene result in an overactive signaling function triggering uncontrolled cell division. Mutations of the RET gene resulting in gain of function are associated with multiple endocrine neoplasia types IIA and IIB, medullary thyroid carcinoma, pheochromocytoma and parathyroid tumors. Rearrangements with over 15 different partners have been identified. 

Empire Genomics has developed a custom RET probe which can be used to detect/confirm a rearrangement of the RET gene. The probe comes labeled in orange, and generally ships within 24 hours. You can choose to customize the probe to meet your needs, which will ship right after production of the probe is complete (approximately 1 week).

Probe Details

Gene:	RET (Orange 5-TAMRA dUTP)
Loci:	10q11
Test Kits:	20

The leading supplier of molecular diagnostics for customization and production of FISH probes, aGCH assays and upcoming new technologies to be used by Reference labs, Academic labs, Pharma, CRO’s
and Pharma /Biotech companies around the world.

Our companion Diagnostics will allow you to :
-Validate Bio-markers (signature identification and resistance).
-Identify and qualify the aberration at the Chromosomal level of specific population.
-Follow up the result of therapeutic treatment (monitoring, compound profiling, drug response, patient stratification and safety)
-Compare with the result of your current technology.
-Be translated into the initial phase of your diagnostics development toward new FDA filings (pre-clinical through clinical trial development).