The PTEN gene encodes the phosphatase and tensin homolog protein that plays a role in multiple cell processes, including growth, proliferation, survival, and maintenance of genomic integrity. Mutations of this gene are a step in the development of many cancers. PTEN is one of the most commonly lost tumor suppressors in human cancer. Frequent genetic inactivation of PTEN occurs in glioblastoma, endometrial cancer, and prostate cancer; and reduced expression is found in many other tumor types such as lung and breast cancer. 

Empire Genomics has developed a custom PTEN probe which can be used to detect/confirm a rearrangement of the PTEN gene. The probe comes labeled in orange and generally ships within 24 hours. You can choose to customize the probe to meet your needs, which will ship right after production of the probe is complete (approximately 1 week).

Probe Details

Gene:	PTEN (Orange 5-TAMRA dUTP)
Loci:	10q23
Test Kits:	20

 

The leading supplier of molecular diagnostics for customization and production of FISH probes, aGCH assays and upcoming new technologies to be used by Reference labs, Academic labs, Pharma, CRO’s
and Pharma /Biotech companies around the world.

Our companion Diagnostics will allow you to :
-Validate Bio-markers (signature identification and resistance).
-Identify and qualify the aberration at the Chromosomal level of specific population.
-Follow up the result of therapeutic treatment (monitoring, compound profiling, drug response, patient stratification and safety)
-Compare with the result of your current technology.
-Be translated into the initial phase of your diagnostics development toward new FDA filings (pre-clinical through clinical trial development).