FGFR1 gene encodes one member of the FGFR tyrosine kinase (TK) family, which includes four kinases: FGFR1, 2, 3, and 4. FGFR TKs play crucial roles in development and have been shown in cancers to be deregulated by either amplification, point mutation, or translocation. Amplification or activation of FGFR1 has been reported in many cancers including oral squamous cell carcinoma, breast cancer, esophageal squamous cell carcinoma, ovarian cancer, bladder cancer, prostate cancer, and lung cancer, predominantly in the squamous subtype. 

Empire Genomics has developed a custom FGFR1 probe which can be used to detect/confirm a rearrangement of the FGFR1 gene. The probe comes labeled in orange, and generally ships within 24 hours. You can choose to customize the probe to meet your needs, which will ship right after production of the probe is complete (approximately 1 week).

Probe Details

Gene:	FGFR1 (Orange 5-TAMRA dUTP)
Loci:	8p11
Test Kits:	20

The leading supplier of molecular diagnostics for customization and production of FISH probes, aGCH assays and upcoming new technologies to be used by Reference labs, Academic labs, Pharma, CRO’s
and Pharma /Biotech companies around the world.

Our companion Diagnostics will allow you to :
-Validate Bio-markers (signature identification and resistance).
-Identify and qualify the aberration at the Chromosomal level of specific population.
-Follow up the result of therapeutic treatment (monitoring, compound profiling, drug response, patient stratification and safety)
-Compare with the result of your current technology.
-Be translated into the initial phase of your diagnostics development toward new FDA filings (pre-clinical through clinical trial development).