These fluorescence in situ hybridization (FISH) probes are intended to detect reciprocal translocations [t(11;14)(q13;q32)] involving the CCND1 and IGH gene regions. This is one of the most common translocation events detected in myeloma. Patients with this translocation have been reported to have better survival and respond favorably to treatment, specifically high dose therapy and stem cell transplantation. 

Empire Genomics has developed a custom CCND1-IGH probe which can be used to detect/confirm a rearrangement of the CCND1-IGH genes. The probe comes labeled in orange and green, and generally ships within 24 hours. You can choose to customize the probe to meet your needs, which will ship right after production of the probe is complete (approximately 1 week).

Probe Details

Genes:	CCND1 (Orange 5-TAMRA dUTP) IGH (Green 5-Fluorescein dUTP)
Loci:	11q13 14q32
Test Kits:	20

The leading supplier of molecular diagnostics for customization and production of FISH probes, aGCH assays and upcoming new technologies to be used by Reference labs, Academic labs, Pharma, CRO’s
and Pharma /Biotech companies around the world.

Our companion Diagnostics will allow you to :
-Validate Bio-markers (signature identification and resistance).
-Identify and qualify the aberration at the Chromosomal level of specific population.
-Follow up the result of therapeutic treatment (monitoring, compound profiling, drug response, patient stratification and safety)
-Compare with the result of your current technology.
-Be translated into the initial phase of your diagnostics development toward new FDA filings (pre-clinical through clinical trial development).