MERTK is a member of the MER/AXL/TYRO3 receptor kinase family and encodes a transmembrane protein with two fibronectin type-III domains, two Ig-like C2-type (immunoglobulin-like) domains, and one tyrosine kinase domain. Mutations in MERTK have been associated with disruption of the retinal pigment epithelium (RPE) phagocytosis pathway and onset of autosomal recessive retinitis pigmentosa (RP).
Rat Tyrosine-protein kinase Mer (MERTK) ELISA Kit employs a two-site sandwich ELISA to quantitate MERTK in samples. An antibody specific for MERTK has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and anyMERTK present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for MERTK is added to the wells. After washing, Streptavidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of MERTK bound in the initial step. The color development is stopped and the intensity of the color is measured.
Rat Tyrosine-protein kinase Mer (MERTK) ELISA Kit listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Find more details at http://www.abbkine.com/product/rat-tyrosine-protein-kinase-mer-mertk-elisa-kit-kte100634/
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