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AMSBIO:Custom Phospho-Specific Antibody Production Service

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Drawing upon many years鈥 experience, AMSBIO has developed a custom phospho-specific antibody production service that is both reliable and produces highly specific quality antisera.

Phospho-specific antibodies are widely accepted for use in defining regulatory mechanisms that control cell functions such as activation of enzymes and receptors, cellular transcription, signal transduction, and cell signalling networks. Phospho-specific antibodies from AMSBIO are affinity-purified rabbit polyclonal or monoclonal antibodies that are monospecific for a target protein that is phosphorylated on a specific tyrosine, threonine, or serine residue.

AMSBIO:Custom Phospho-Specific Antibody Production Service

AMSBIO鈥檚 custom phospho-specific polyclonal antibody service includes synthesis of phosphorylated and non-phosphorylated peptides, conjugation to a carrier protein, immunization and anti-sera production. All antibodies are then purified using a two-step immuno-affinity method. The purified phospho-specific antibody is fully characterised using both dot-blot and ELISA techniques to ensure product of the highest consistency and quality. Hundreds of custom phospho specific antibodies have been successfully made by AMSBIO and supplied to leading international research groups [1,2].

For further information on please visit http://www.amsbio.com/Custom-Phospho-Specific-Polyclonal-Antibody-Service.aspx or contact AMSBIO now on +44-1235-828200 / +1-949-768-8365 or email info@amsbio.com.

Founded in 1987, AMS Biotechnology (AMSBIO) is recognized today as a leading company contributing to the acceleration of discovery through the provision of cutting-edge life science technology products and services for research and development in the medical, nutrition, cosmetics and energy industries. The AMSBIO range includes specialist antibodies, peptides and recombinant proteins. In addition the company is able to draw upon in-depth expertise in extracellular matrices to provide elegant solutions for studying cell motility, migration, invasion and proliferation. Widely acknowledged as experts in cell culture, AMSBIO partners with clients in tailoring cell systems to enhance screening outcomes and eventual prognosis. With a range of molecular detection reagents, and a significant Biorepository the company can also provide tissue DNA, RNA, protein and microarray products. Key research areas for these products include: Oncology, Regenerative Medicine, Environmental Analysis, Cytotoxicity Screening, Glycomics and Stem Cell Biology.

Ref 1: Brain Human Monoclonal Autoantibody from Sydenham Chorea Targets Dopaminergic Neurons in Transgenic Mice and Signals Dopamine D2 Receptor: Implications in Human Disease CJ Cox, M Sharma, JF Leckman, J Zuccolo, A Zuccolo鈥 - The Journal of Immunology, 2013 (http://www.jimmunol.org/content/early/2013/11/01/jimmunol.1102592.abstract)

Ref 2: Cyclic AMP-specific phosphodiesterase, PDE8A1, is activated by protein kinase A-mediated phosphorylation KM Brown, LCY Lee, JE Findlay, JP Day, GS Baillie - Febs Letters, 2012 - Elsevier (http://www.sciencedirect.com/science/article/pii/S0014579312003225


Worldwide HQ

AMS Biotechnology (AMSBIO)
184 Milton Park
Oxon OX14 4SE
Tel: +44-1235-828200
Fax: +44-1235-820482
Email: info@amsbio.com
Web www.amsbio.com

North American HQ

23591 El Toro Road, Suite#180
Lake Forest, CA 92630
Tel: +1-800-987-0985
Email: info@amsbio.com

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