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A Sound Combination for Superior Miniaturised Assay Preparation

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Titian鈥檚 Mosaic sample management software seamlessly integrates with Labcyte automation and Echo® liquid handlers.

LONDON, UK (9 January 2013): Leading sample management software provider, Titian Software, and Labcyte Inc., have announced a smart integration of the Mosaic sample management suite with the AccessTM workstation and PODTM automation platform 鈥 two Labcyte automation systems incorporating their revolutionary Echo® liquid handler.  The combination of Mosaic鈥檚 powerful software and flexible integration modules, coupled with the Echo system鈥檚 low volume acoustic liquid handling, enable fast, accurate, cost effective and fully traceable automated workflows for high-quality assay development and miniaturisation.

Edmund Wilson, CEO of Titian, commented; 鈥淲e have been working in close collaboration with the team at Labcyte to integrate the Mosaic web-based sample ordering facilities to the Access workstation鈥. He continued; 鈥淥ne of the key objectives was to give users the convenience of requesting low volume assay-ready plates, with these being prepared automatically with very high precision.鈥
Mosaic easily and efficiently manages and tracks sample libraries with improved sample preservation and viability. Requestors can select individual substances, plates or substance sets for assay. Mosaic allows assay plate formats to be defined and easily managed. Mosaic requests can also be configured as templates to precisely and repeatedly match the requirements of particular assays. The order workflow is managed, ensuring that the correct items are brought to Labcyte systems to begin assay-ready plate preparation.
Labcyte automation systems incorporate Echo liquid handlers into small- and large- scale systems for walk-away sample processing.  Since the Echo liquid handler does not require the use of pipette tips, pin tools or nozzles it provides unsurpassed precision and accuracy. With a range of device options and accessories, Labcyte automation systems adapt to the ever鈥恈hanging needs of assays in drug discovery, genomics, proteomics, and more.
Titian provides a driver module that transfers instruction files to the Labcyte Tempo automation control software 鈥 an intuitive platform to develop protocols for the Access and POD systems. At the end of each acoustic transfer, the resulting changes in the inventory (including acoustic surveys of source well contents) are reflected in Mosaic, using the results data generated on the Labcyte systems, without operator interaction.
Labcyte Tempo software manages all tasks including system setup as well as all plate and liquid handling activities. After plate loading and sample transfer, the assay ready plates are sealed or lidded and stacked ready for delivery. In addition to low volume plate replication and hit picking, the ability of the Echo system to transfer samples in as little as 2.5 nL permits a direct dilution of samples for dose-response assays; eliminating the cross-contamination and error propagation seen with traditional serial dilution methods.
鈥淲e have integrated our Echo liquid handler, automation, software, and consumables into cost-effective, high performance solutions targeting a range of applications,鈥 says Mark Fischer鈥怌olbrie, CEO and president of Labcyte. 鈥淭he collaboration with Titian and their Mosaic software suite will allow our customers to seamlessly integrate sample management, processing, and analysis while improving results and saving costs.鈥
Titian Software is continually expanding the capabilities of the Mosaic sample management suite to meet current demands and, more importantly, new application developments. For more information please visit the Titian Software website, www.titian.co.uk.
Labcyte developed and commercialized acoustic liquid transfer and continues to deliver innovative solutions with unsurpassed quality and efficiency.   For more information visit our website, www.labcyte.com.
Established in 1999, Titian supplies software products and consultancy services that help clients to improve the management of samples (compounds, reagents and biological samples) for their vital research processes. 13 of the Top 20 pharma/biotech companies have chosen Titian鈥檚 Mosaic sample management technologies to provide increased sample quality, service levels, and sample conservation while reducing overall operating cost and time.
Mosaic 鈥 modular sample management software
Mosaic is Titian Software鈥檚 comprehensive, modular software product to control and monitor all aspects of sample storage and preparation. These include sample inventory tracking and ordering, workflow management, control of third party robotic equipment such as automated stores and liquid handlers, and integration with existing IT systems. From small biotech to global pharma, Mosaic helps to provide a seamless, error-free sample supply chain.
Consultancy Services
Titian provides strategic and technical consultancy to help life science research organisations optimize their sample management processes. Building on over 10 years of experience and extensive knowledge of industry best practice, Titian offers consultancy services including user requirements capture, process mapping and re-engineering, and software system implementation.
Labcyte, a global biotechnology tools company headquartered in Sunnyvale, California, is revolutionizing liquid handling. Echo liquid handling systems use sound to precisely transfer liquids without contact and can therefore eliminate the use of pipettes. Labcyte instruments are used worldwide throughout the pharmaceutical industry, as well as by biotechnology firms, contract research organizations, and academic institutions. Labcyte鈥檚 customers work across a wide spectrum of scientific research, including drug discovery, genomics, proteomics, diagnostics, personalized medicine and imaging mass spectrometry. Labcyte has 62 U.S. patents, European, Japanese and Chinese patents with additional U.S. and international filings. For more information, visit www.labcyte.com.
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